Wholesale Factory Supply High Purity 2,2-Difluoropropionic acid 373-96-6 Cheapest Price
- Molecular Formula:C3H4F2O2
- Molecular Weight:110.06
- Vapor Pressure:1940mmHg at 25°C
- Melting Point:41-44 °C
- Refractive Index:1.313
- Boiling Point:136.957 °C at 760 mmHg
- PKA:1.34±0.10(Predicted)
- Flash Point:36.63 °C
- PSA：37.30000
- Density:1.316 g/cm3
- LogP:0.72620
2,2-Difluoropropionic acid(Cas 373-96-6) Usage
|
Chemical Properties
|
White powder |
InChI:InChI=1/C4H5F3/c1-3(2)4(5,6)7/h1H2,2H3
373-96-6 Relevant articles
Α, α-difluoropropionic production of esters
-
Paragraph 0123-0125, (2016/10/10)
PROBLEM TO BE SOLVED: To provide a pract...
MEDICINAL COMPOSITIONS
-
, (2008/06/13)
The present invention relates to an agen...
Substituted 1,3-thiazole compounds, their production and use
-
, (2008/06/13)
(1) A 1,3-thiazole compound of which the...
Antidiabetic agents
-
, (2008/06/13)
The instant invention is concerned with ...
373-96-6 Process route
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-
108221-67-6
ethyl 2-bromo-2-fluoropropionate
-
-
373-96-6
2,2-difluoropropanoic acid
-
-
760-80-5
ethyl 2-fluoroacrylate
-
-
28781-85-3
ethyl 2,2-difluoropropanoate
Conditions
| Conditions |
Yield |
|
With
2,6-di-tert-butyl-4-methyl-phenol; pyridine hydrogenfluoride; 1,8-diazabicyclo[5.4.0]undec-7-ene;
at 20 ℃;
for 48h;
Cooling with ice;
|
64%
9%
27%
|
-
-
methyl α-bromo-α-fluoropropionate
-
-
2343-89-7
methyl 2-fluoroprop-2-enoate
-
-
373-96-6
2,2-difluoropropanoic acid
-
methyl 2,2-difluoropropionate
-
38650-84-9
methyl 2,2-difluoropropionate
Conditions
| Conditions |
Yield |
|
With
2,6-di-tert-butyl-4-methyl-phenol; hydrogen fluoride; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
acetonitrile;
at 50 ℃;
for 72h;
Reagent/catalyst;
Solvent;
Temperature;
Cooling with ice;
|
70%
18%
5%
|
373-96-6 Upstream products
373-96-6 Downstream products
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1000587-70-1
3-(2,2-difluoropropionylamino)-5-(5-methylpyridin-2-yl)benzoic acid methyl ester
-
849351-86-6
N-{5-[acetyl(methyl)amino]-2-[(tetrahydro-2H-pyran-4-ylmethyl)amino]phenyl}-2,2-difluoropropanamide
-
881417-92-1
N-[2-(1,1-difluoroethyl)-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]acetamide
-
49781-48-8
2,2-difluoropropionamide
