27025-41-8

  • Product NameGlutathiol
  • Molecular FormulaC20H32N6O12S2
  • Molecular Weight640.693
  • Purity99%
  • AppearanceWhite lyophilized powder
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Product Details

Quick Details

  • CasNo: 27025-41-8
  • Molecular Formula: C20H32N6O12S2
  • Appearance: White lyophilized powder
  • Purity: 99%

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  • Molecular Formula:C20H32N6O12S2
  • Molecular Weight:640.693
  • Appearance/Colour:White lyophilized powder 
  • Vapor Pressure:0mmHg at 25°C 
  • Melting Point:178 °C (dec.)(lit.) 
  • Refractive Index:-105 ° (C=2, H2O) 
  • Boiling Point:1196.497 °C at 760 mmHg 
  • PKA:2.12, 3.59, 8.75, 9.65(at 25℃) 
  • Flash Point:677.417 °C 
  • PSA:368.24000 
  • Density:1.54 g/cm3 
  • LogP:-0.91260 

L(-)-Glutathione(Cas 27025-41-8) Usage

Description

L-Glutathione oxidized is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of it. It can be used for the research of sickle cells and erythrocytes.

Chemical Properties

White lyophilized powder

Uses

L(-)-Glutathione is a biomarker for fatty liver disease.

Application

L-Glutathione (GSH) has been used in the elution buffer to elute GST (glutathione S-transferase)-fused proteins using glutathione-agarose beads. It has been used to prepare a standard curve for GSH analyses. May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.

Biochem/physiol Actions

L-Glutathione, oxidized is frequently measure in vivo as an indicator of oxidative stress. Oxidized L-Glutathione may be converted to L-glutathione by various reducing systems.

Purification Methods

Purify it by recrystallisation from 50% aqueous EtOH. Its solubility in H2O is 5%. Store it at 4o. [Li et al. J Am Chem Soc 76 225 1954, Berse et al. Can J Chem 37 1733 1959, Beilstein 4 IV 3168.]

InChI:InChI=1/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/t9-,10-,11-,12-/m0/s1

27025-41-8 Relevant articles

The thiol-based reduction of Bi(V) and Sb(V) anti-leishmanial complexes

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27025-41-8 Process route

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Oxidized glutathione

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Conditions
Conditions Yield
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Cumene hydroperoxide
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Oxidized glutathione
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Conditions
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