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What is the L-Carnosine ?
L-Carnosine is crystalline, while it's Molecular Formula is C9H14N4O3. carnosine is an anti-oxidant that works to prevent cellular damage because of free radical activity. Studies indicate an ability to boost the immunological functions. Carnosine is a naturally occurring amino acid. In cosmetics, it has anti-aging and skin-conditioning applications.
What is the CAS number for L-Carnosine ?
The CAS number of L-Carnosine is 305-84-0.
More information of L-Carnosine 305-84-0 are:
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Synonyms
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beta-Alanyl-L-histidine;L-Carnosine 99% min.;N-2-M;L-Carnosinc;β-Alanyl-L-histidine;L-Carnosine Acetate;Karnozin;2-(3-aminopropanoylamino)-3-(3H-imidazol-4-yl)propanoic acid;L-Histidine, N-.beta.-alanyl-;Nalpha-(beta-alanyl)-L-histidine;(2S)-2-(3-aminopropanoylamino)-3-(3H-imidazol-4-yl)propanoic acid;.beta.-Alanyl-L-histidine;Ignotine; |
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CAS Number
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305-84-0 |
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Molecular Formula
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C9H14N4O3 |
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Molecular Weight
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226.235 |
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Density
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1.41 g/cm3 |
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Melting Point
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253 °C (dec.)(lit.) |
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Boiling Point
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511.7 °C at 760 mmHg |
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Flash Point
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263.3 °C |
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HS CODE
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29332900 |
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PSA
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121.10000 |
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LogP
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-0.03840 |
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Pka
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2.62(at 25℃) |
What is L-Carnosine (305-84-0) used for?
L-Carnosine is a dipeptide composed of β-alanine and L-histidine that has been found in rat olfactory bulb, skeletal muscle, brain, kidney, and spleen tissues, as well as human skeletal muscle, and has diverse biological activities. It is a metal chelator that forms complexes with copper, cobalt, nickel, cadmium, or zinc. Dietary administration of L-carnosine (60 mg/kg per day) reduces plasma levels of advanced glycation end products (AGEs) in diabetic rats. It reduces brain edema, blood-brain barrier disruption, microglial activation, and neuronal apoptosis in a rat model of intracerebral hemorrhage when administered at a dose of 1,000 mg/kg. L-Carnosine (250, 500, and 1,000 mg/kg, i.p.) reduces hepatic protein carbonylation and necrosis in a rat model of cirrhosis induced by bile duct ligation. It also reduces lung myeloperoxidase (MPO) activity, production of reactive oxygen species (ROS), and TNF-α and IL-6 levels, as well as alveolar hemorrhage, interstitial edema, and pulmonary leukocyte infiltration in a mouse model of LPS-induced lung injury.
InChI:InChI=1/C9H14N4O3/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6/h4-5,7H,1-3,10H2,(H,11,12)(H,13,14)(H,15,16)/t7-/m0/s1
Articles related to L-Carnosine:
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Article
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Source
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Molecular identification of carnosine synthase as ATP-grasp domain-containing protein 1 (ATPGD1)
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Drozak, Jakub,Veiga-da-Cunha, Maria,Vertommen, Didier,Stroobant, Vincent,Van Schaftingen, Emile
, p. 9346 - 9356 (2010)
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-
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Kroll,Hoberman
, p. 2511 (1953)
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