Buy High Quality High Purity 99% Ethyl 2,2-Difluoropropionate 28781-85-3 In Stock
- Molecular Formula:C5H8F2O2
- Molecular Weight:138.114
- Refractive Index:1.351
- Boiling Point:97.2 °C at 760 mmHg
- Flash Point:13.4 °C
- PSA：26.30000
- Density:1.1 g/cm3
- LogP:1.20470
28781-85-3 Relevant articles
METHOD FOR MANUFACTURING DIFLUOROMETHYLENE COMPOUND
-
Paragraph 0204-0207, (2020/03/28)
The problem to be solved by the present ...
METHOD FOR PREPARING FLUOROORGANIC COMPOUNDS
-
Paragraph 0153, (2020/08/12)
A process for preparing a compound of fo...
Α, α-difluoropropionic production of esters
-
Paragraph 0123-0125, (2016/10/10)
PROBLEM TO BE SOLVED: To provide a pract...
Synthesis of fluorinated and nonfluorinated tebufenpyrad analogues for the study of anti-angiogenesis MOA
Roman, Raquel,Navarro, Antonio,Wodka, Dariusz,Alvim-Gaston, Maria,Husain, Saba,Franklin, Natalie,Simon-Fuentes, Antonio,Fustero, Santos
, p. 1027 - 1036 (2014/10/15)
In this contribution we report the synth...
28781-85-3 Process route
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- 617-35-6
2-oxo-propionic acid ethyl ester
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- 28781-85-3
ethyl 2,2-difluoropropanoate
Conditions
| Conditions |
Yield |
|
With (bis-(2-methoxyethyl)amino)sulfur trufluoride; at -15 - 30 ℃;
|
99.4% |
|
With sulfur tetrafluoride; In hydrogen fluoride; at 20 ℃; for 12h; steel autoclave;
|
78% |
|
With diethylamino-sulfur trifluoride; at 60 ℃; for 4h;
|
62.3% |
|
With diethylamino-sulfur trifluoride; for 18h; Ambient temperature;
|
60.9% |
|
With (diethylamido)sulfur trifluoride; at 0 ℃; for 0.5h;
|
52% |
|
With sulfur tetrafluoride;
|
|
|
With trans-4,4'-diaminostilbene-2,2'-disulfonic acid; In dichloromethane; water;
|
|
|
With (bis-(2-methoxyethyl)amino)sulfur trufluoride; In dichloromethane; toluene; at 20 ℃;
|
|
|
With diethylamino-sulfur trifluoride; at 0 - 20 ℃;
|
55.6 g |
|
With (bis-(2-methoxyethyl)amino)sulfur trufluoride; In ethanol; dichloromethane;
|
|
|
With disulfur dichloride; C5H5N*(x)FH*F5I; In dichloromethane; at 20 - 70 ℃; for 1.33333h; under 3000.3 Torr; Reagent/catalyst; Pressure; Temperature; Autoclave;
|
|
-
- 373-96-6
2,2-difluoropropanoic acid
-
- 28781-85-3
ethyl 2,2-difluoropropanoate
Conditions
| Conditions |
Yield |
|
With sulfuric acid; In cyclohexene; at 80 ℃; for 6h; under 760.051 Torr; Inert atmosphere;
|
|
28781-85-3 Upstream products
-
64-17-5
ethanol
-
28781-87-5
2-Fluor-propionyl-fluorid
-
617-35-6
2-oxo-propionic acid ethyl ester
-
38078-09-0
diethylamino-sulfur trifluoride
28781-85-3 Downstream products
-
144464-70-0
α,α-difluoro-p-methoxypropiophenone
-
136101-46-7
2,2-Difluoro-1-[4-(4-heptyl-cyclohexyl)-phenyl]-propan-1-one
-
136101-47-8
2,2-Difluoro-1-[4-(4'-propyl-bicyclohexyl-4-yl)-phenyl]-propan-1-one
-
136101-48-9
2,2-Difluoro-1-[4'-(4-pentyl-cyclohexyl)-biphenyl-4-yl]-propan-1-one
